What is HPFH?

Hereditary Persistence of Fetal Haemoglobin (HPFH) is a term used to describe the genetically determined persistence of fetal haemoglobin production into adult life. The condition is inherited from one parent that has at least one gene for the HPHF. The individual that carries HPHF is not anaemic and there are no clinincal or haematological abnormalities associated with this condition.

When an individual carries both beta thalassaemia and HPFH the combination cannot cause anaemia. It is important that if this individual decides to have children they should have their partner tested for haemoglobin disorders.

If you would like further information on this condition please follow this link Carrying HPFH